Sophia Children's Hospital | Research

Research groups (15)

S. Pasmans

Atopic derma­titis & the Atopic­ syndrome

Atopic dermatitis is the commonest chronic skin disease in children. It is mild in about 70% of cases, moderate in 25% and severe in 5%.

P.F.A. de Nijs

Autism Spectrum Disorder

We disentangle the autism spectrum phenotype using various diagnostic approaches, relate the core problems to frequent other problems, and explore developmental courses.

R.M.W. Hofstra

GI-Genetics Hirschsprung disease (HSCR)

Which genetic factors determine the development of the gastrointestinal (GI) tract, and how do these genetic factors contribute to disease development?

S. Pasmans

Immune­dysregula­tion in atopic skin diseases

Atopic dermatitis and Netherton syndrome might be systemic diseases like primary immunodeficiencies (PIDs).

H.A.W.M. Tiddens

LungAnalysis Core Lab

LungAnalysis is an image analysis laboratory of the Erasmus Lung Imaging Group.

A.T. van der Ploeg

Lysosomal and Metabolic Diseases - Clinical Research

Lysosomal and metabolic diseases are rare genetic disorders caused by metabolic enzyme deficiency.

T.J. van Ham

Macrophages in the healthy and diseased brain

Mutations in genes important for microglia, the brain’s macrophages, can predispose to brain diseases such as Alzheimer’s. The underlying mechanisms are largely unknown.

P. Pijnappel

Molecular stem cell biology of lysosomal storage diseases

These diseases are rare genetic disorders caused by a deficiency of metabolic enzymes. Metabolic products accumulate throughout the body, affecting multiple organs and tissues.

C.C.W. Klaver

Myopia (nearsightedness)

Our research groups investigates how a complex interplay between genetic and environmental factors leads to high myopia and how this can be prevented.

T.S. Barakat

Non-Coding Genome in Neurodevelopmental Disorders

Our group focuses on deciphering the role of the non-coding genome in gene regulation, specifically addressing human embryonic stem cells and neurodevelopment.

J. Samsom

Pediatric Gastroenterology & Nutrition - Samsom lab

Which immune regulatory processes are essential to develop and maintain the intestinal immune system’s tolerance to dietary antigens and commensal bacteria?

W. Unger

Pediatric Infection and Immunity

Pneumonia is the number one cause of mortality in children. We aim to improve the diagnostics to prevent inappropriate antibiotics use.

L. Utens

Pediatric psychology

Pediatric psychology entails practice, targeting the psychology of illness and injury, and promoting health behaviors in children, adolescents and families.

S. Pasmans

Rare Skin Diseases

Children may be affected by a wide range of rare skin diseases, the care and cure of which are little known.

S. Pasmans

Vascular Anomaly Center

We perform clinical research on vascular anomalies such as hemangioma, kaposiform hemangioendothelioma and capillary, venous, and lymphatic malformations.